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Ion chromatography mass spectrometry icms thermo fisher. This paper describes the development of an analytical procedure to determine malachite green mg residues in salmon samples using molecularly imprinted polymers mips as the extraction and cleanup material, followed by liquid chromatography linear ion trap mass spectrometry lcqqqlitmsms. Mass spectrometry is a wideranging analytical technique, which involves the production and subsequent separation and identification of charged species. It is a powerful analytical technique that combines the resolving power of liquid chromatography with the detection specificity of mass spectrometry. In recent years, liquid chromatography lc coupled to mass spectrometry ms or tandem mass spectrometry msms has become increasingly important in the. Liquid chromatographymass spectrometry lcms, or alternatively hplcms is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography or hplc with the mass analysis capabilities of mass spectrometry. Recent advance in liquid chromatography mass spectrometry. Ppt column chromatography powerpoint presentation free to. Figure 2 shows the identification of a cdiglycoside through ms 2 experiments in an it ftms instrument. The high performance liquid chromatography hplc training video describes the components of a hplc system by introducing each part of a typical instrument in terms of the role. Lcms is becoming an increasingly indispensable tool in many application fields. Introduction the centers for disease control and prevention report that nearly three out of four prescription drug overdoses involve prescription pain killers1 and that death rates involving opioid analgesic abuses have more than tripled in the u. Fundamental lcms principle guide shimsolutions club. A brief guide to hplc instruments from mourne training services.
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